Original Research, Reviews, Research Highlights, and Commentaries/Editorials

Boettcher A.N., Schachtschneider K.M., Schook, L.B., and Tuggle C.K. Swine Models for Translational Oncological Research: An Evolving Landscape and Regulatory Considerations. Submitted May 2021. Under review at Mammalian Genome.
Boettcher A.N. Research Highlight: Somatostatin Receptor Type 2 as an Imaging and Treatment Target for Thyroid Cancer. 2021. Radiology: Imaging Cancer. 2021. 3:3
Luker G.D. and Boettcher. A.N. Impact of COVID-19 on Clinical Care and Research in Cancer Imaging: Where We Are Now. Radiology: Imaging Cancer. 2021. 3:2
Boettcher. A.N. Research Highlight: Preclinical Evaluation of a Granzyme B PET Tracer for the Assessment of Immunotherapy Response. Radiology: Imaging Cancer. 2021. 3:1
Boettcher. A.N., Hammoud D.A., Weinberg J.B., Agarwal P., Mendiratta-Lala M., and Luker G.D. Cancer Imaging and Patient Care during the COVID-19 Pandemic. 2020. Radiology: Imaging Cancer. 2:6
Boettcher. A.N. Research Highlight: ImmunoPET: Development of a Radiotracer to Monitor Inducible T-cell Costimulator Expression in Response to Immunotherapy. 2020. Radiology: Imaging Cancer 2:5
Boettcher. A.N. Research Highlight:  Preclinical Assessment of the Safety of an 18F-labeled MCT1/MCT4 Inhibitor in a Swine Model for PET/CT Imaging of Cancer Metabolism. 2020. Radiology: Imaging Cancer 2:4
Boettcher A.N. Research Highlight: Preclinical Model of Optical Coherence Tomography for High-Resolution Deep-Brain Imaging for Laser Ablation. 2020. Radiology: Imaging Cancer 2:3
Luker, G.D and Boettcher, A.N. Transitioning to a New Normal After COVID-19: Preparing to Get Back on Track for Cancer Imaging. 2020 Radiology: Imaging Cancer 2:3
Boettcher, A.N. Research Highlight: Development and Characterization of B7-H3 specific Affibody-coated Microbubbles for Breast US Imaging. Radiology: Imaging Cancer. 2:2 
Boettcher, A.N, Cino-Ozuna, G.A., Solanki, Y., Wiarda, J.E., Putz, E.J., Owens, J.L., Crane, S.A., Ahrens, A.P., Loving, C.L., Cunnick, J.E., Rowland, R.R.R., Charley, S.E., Dekkers, J.C.M., Tuggle, C.K. (2020). CD3+ Cells in Pigs with Severe Combined Immunodeficiency Due to Defects in Artemis. Front. Immunol. 11, 510.
Boettcher, A.N., Li, Y., Ahrens, A.P., Kiupel, M., Byrne, K.A., Loving, C.L., Cino-Ozuna, A.G., Wiarda, J.E., Adur, M., Schultz, B., Swanson, J.J., Snella, E.M., Ho, C.-S. (Sam), Charley, S.E., Kiefer, Z.E., Cunnick, J.E., Putz, E.J., Dell’Anna, G., Jens, J., Sathe, S., Goldman, F., Westin, E.R., Dekkers, J.C.M., Ross, J.W., and Tuggle, C.K. (2020) Novel Engraftment and T Cell Differentiation of Human Hematopoietic Cells in ART−/−IL2RG−/Y SCID Pigs   . Front. Immunol.  , 11, 100.
Boettcher, A.N. Research Highlight: Near-Infrared Labeling of EGFR+ Cells Can Allow Differentiation between Benign and Metastatic Lymph Nodes. Radiology: Imaging Cancer, 2:1. 
Boettcher, A.N., Usman, A., Morgans, A.K., Vanderweele, D., Sosman, J., and Wu, J.D. (2019) Past, current, and future of immunotherapies for prostate cancer. Front. Oncol., 9, 884
Boettcher, A.N., Ahrens, A.P., Charley, S.E., and Tuggle, C.K. (2019) A Comprehensive Protocol for Laparotomy in Swine to Facilitate Ultrasound-Guided  Injection into the Fetal Intraperitoneal Space. Comp. Med., 69 (2), 123–129.​
Boettcher, A.N., Kiupel, M., Adur, M.K., Cocco, E., Santin, A.D., Bellone, S., Charley, S.E., Blanco-Fernandez, B., Risinger, J.I., Ross, J.W., Tuggle, C.K., and Shapiro, E.M. (2019) Human Ovarian Cancer Tumor Formation in Severe Combined Immunodeficient (SCID) Pigs. Front. Oncol., 9, 9.
Boettcher, A.N., Loving, C.L., Cunnick, J.E., and Tuggle, C.K. (2018) Development of Severe Combined Immunodeficient (SCID) Pig Models for Translational Cancer Modeling: Future Insights on How Humanized SCID Pigs Can Improve Preclinical Cancer Research. Front. Oncol., 8, 559.
Boettcher, A.N., Cunnick, J.E., Powell, E.J., Egner, T.K., Charley, S.E., Loving, C.L., and Tuggle, C.K. (2018) Porcine signal regulatory protein alpha binds to human CD47 to inhibit phagocytosis: Implications for human hematopoietic stem cell transplantation into severe combined immunodeficient pigs. Xenotransplantation, e12466.
Powell, E.J., Graham, J., Ellinwood, N.M., Hostetter, J., Yaeger, M., Ho, C.-S., Gault, L., Norlin, V., Snella, E.N., Jens, J., Waide, E.H., Boettcher, A.N., Kerrigan, M., Rowland, R.R.R., Ross, J.W., Dekkers, J.C.M., and Tuggle, C.K. (2017) T Cell Lymphoma and Leukemia in Severe Combined Immunodeficiency Pigs following Bone Marrow Transplantation: A Case Report. Front. Immunol., 8, 813.​
Powell, E.J., Charley, S., Boettcher, A.N., Varley, L., Brown, J., Schroyen, M., Adur, M.K., Dekkers, S., Isaacson, D., Sauer, M., Cunnick, J., Ellinwood, N.M., Ross, J.W., Dekkers, J.C., and Tuggle, C.K. (2018) Creating effective biocontainment facilities and maintenance protocols for raising specific pathogen-free, severe combined immunodeficient (SCID) pigs. Lab. Anim., 23677217750691.


Welcome to the Radiology: Imaging Cancer Podcast (May 2020)

Preclinical and Translational Cancer Imaging Research (January 2021)

A year into the COVID-19 pandemic: challenges and outlooks for the cancer imaging community (April 2021)

A Multifaceted View of Cancer Imaging, Diagnosis, and Treatment (June 2021)

Outreach Pieces
1. Video: Transitioning to a New Normal After COVID-19: Preparing to Get back on Track for Cancer Imaging  (Radiology: Imaging Cancer)
2. Geeky Girl Reality Blog : Meet Dr. Addie 
3. Introducing Adeline Boettcher, Scientific Editor of Radiology: Artificial Intelligence: Vasty Deep Blog
4. Nicole Shea Resilience Blog: A Dissection of a Manuscript: Picking Apart the Pieces to Understand the Building Blocks

PhD Dissertation
Boettcher, Adeline Nicole, "Development and characterization of an immunologically humanized and cancer xenograft model in pigs with severe combined immunodeficiency (SCID)" (2019). Graduate Theses and Dissertations. 16975.
Conferences and Presentations
Past Presentations
Iowa AALAS Branch Annual Meeting- Iowa- 2019
Towards a New Humanized SCID Model: Engraftment of Human Immune Cells after In Utero Injection of Human Hematopoietic Stem Cells
North Central College Biology/Biochemistry Seminar- Illinois- 2018
Development of Severe Combined Immunodeficient Models for Biomedical Research
Academic Career Success Conference by Beyond the Professoriate - Sep 2010
Demystifying the scientific publishing process: How your manuscript becomes a publication